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m-Chlorophenylbiguanide hydrochloride
CAS No. 2113-05-5
m-Chlorophenylbiguanide hydrochloride ( 1-(3-Chlorophenyl)biguanidehydrochloride )
Catalog No. M27652 CAS No. 2113-05-5
m-Chlorophenylbiguanide hydrochloride is a 5-HT3 receptor agonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | 38 | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product Namem-Chlorophenylbiguanide hydrochloride
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NoteResearch use only, not for human use.
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Brief Descriptionm-Chlorophenylbiguanide hydrochloride is a 5-HT3 receptor agonist.
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Descriptionm-Chlorophenylbiguanide hydrochloride is a 5-HT3 receptor agonist. m-Chlorophenylbiguanide hydrochloride selectively binds 5-HT3(Ki: 0.002 μM) over 5-HT1A(Ki: 10 μM) and 5-HT2(Ki: 10 μM) receptors but also binds to high and low affinity sites on the dopamine transporter(DAT; IC50s: 0.4 and 34.8 μM, respectively, in rat caudate putamen synaptosomal membranes).(In Vivo):m-Chlorophenylbiguanide hydrochloride induces depolarization of isolated rat vagus nerve and stimulates inositol phosphate formation in rat frontocingulate cortical slices (EC50s = 0.05 and 4.2 μM, respectively).m-Chlorophenylbiguanide hydrochloride induces bradycardia, an effect that can be reversed by the 5-HT3 receptor antagonist ondansetron, in anaesthetized cats (ED50 = 20.3 nmol/kg).
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Synonyms1-(3-Chlorophenyl)biguanidehydrochloride
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PathwayEndocrinology/Hormones
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Target5-HT Receptor
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number2113-05-5
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Formula Weight248.1
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Molecular FormulaC8H11Cl2N5
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Purity>98% (HPLC)
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Solubility——
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SMILESCl.NC(=N)NC(=N)Nc1cccc(Cl)c1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Tsuji H, Eto T, Sakamoto Y. Synthesis and Hydrolytic Degradation of Substituted Poly(DL-Lactic Acid)s. Materials (Basel). 2011 Aug 10;4(8):1384-1398.
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